{"id":938,"date":"2016-12-22T14:22:22","date_gmt":"2016-12-22T13:22:22","guid":{"rendered":"http:\/\/zavnews.net\/?p=938"},"modified":"2016-12-22T14:22:22","modified_gmt":"2016-12-22T13:22:22","slug":"sada-znamo-sta-nasljedujemo-majke-a-sta-oca","status":"publish","type":"post","link":"https:\/\/zavnews.net\/index.php\/2016\/12\/22\/sada-znamo-sta-nasljedujemo-majke-a-sta-oca\/","title":{"rendered":"Sada znamo \u0161ta naslje\u0111ujemo od majke, a \u0161ta od oca"},"content":{"rendered":"
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Jabuka ne pada daleko od stabla pa od roditelja mo\u017eemo naslijediti brojne fizi\u010dke osobine, ali i bolesti. Od svakog roditelja \u201ckupimo\u201d po dvije kopije svakoga gena, a mutacija odre\u0111enih gena glavni je okida\u010d za nasljedne bolesti.<\/strong>
\nPrvi na popisu je visoki holesterol, za \u0161to u potpunosti mo\u017eemo \u201ckriviti\u201d porodicu, tvdi ameri\u010dka geneti\u010darka dr. Shivani Nazareth.\u00a0<\/strong><\/p>\n

\u2013 Jedan na 500 ljudi ima genetsku mutaciju koja je uzro\u010dnik porodi\u010dne\u00a0hiperholesterolemije<\/strong> \u2013 nasljedne bolesti srca koja mo\u017ee biti uzrokom preuranjenog sr\u010danog ili mo\u017edanog udara \u2013 otkriva Nazareth i dodaje kako oboljeli od porodi\u010dne\u00a0hiperholesterolemije ne mogu regulirati holesterol koji se zato nagomilava u krvnim \u017eilama.<\/p>\n

Ne poma\u017eu \u010dak ni rigorozne dijete ili tjelovje\u017eba jer su u ovom slu\u010daju geni u\u010dinili svoje, ka\u017ee Nazareth.<\/p>\n

I dok oba roditelja mogu biti krivci za visoki holesterol, rak dojke naslje\u0111ujemo od oca<\/strong>. Naime, svaki je \u010dovjek ro\u0111en s genima BRCA1 i BRCA2 koji ne stvaraju zdravstvene probleme dok nisu mutirani. Ali \u017eene koje naslijede mutaciju jednog ili oba BRCA gena od strane oca, imaju ve\u0107i rizik od nastanka raka dojke.<\/p>\n

Doktorica Nazareth pojasnila je kako navedeni geni nisu opasni po zdravlje mu\u0161karaca jer je rak dojke rijetka pojava me\u0111u mu\u0161kom populacijom, dok se isto ne mo\u017ee re\u0107i i za \u017eene.<\/p>\n

\"SlikovniAko za gubitak kose okrivljujete mu\u0161ku stranu porodice\u00a0\u2013 obra\u0107ate se na pogre\u0161nu adresu. Gen koji ima klju\u010dnu ulogu kod \u0107elavosti nalazi se na hromosomu X, koji mu\u0161karci uvijek naslije\u0111uju od majki<\/strong>, dok \u017eene isti gen preuzimaju od oba roditelja.<\/p>\n

\n

\n

Za dijabetes tipa 2 naj\u010de\u0161\u0107e je kriv neuredan na\u010din \u017eivota, no istra\u017eivanja pokazuju da \u010dak 5 posto mladih ima znakove ove bolesti iako nisu debeli i redovno vje\u017ebaju. I ovdje je problem genetska mutacija pa se radi o obliku dijabetesa koji su nau\u010dnici nazvali MODY.<\/p>\n

Rano prepoznavanje pacijenata s MODY podtipom dijabetesa vrlo je va\u017eno jer oni trebaju druga\u010diju terapiju koja mo\u017ee godinama kontrolirati bolest bez pojave komplikacija, ka\u017ee dr. Nazareth.<\/p>\n

No cjelo\u017eivotne komplikacije javljaju se kod intolerancije na laktozu. Priro\u0111ena intolerancija na laktozu rijetka je bolest uzrokovana mutacijom u genu koji proizvodi enzim laktazu. <\/strong>Manifestira se jakim vodenastim proljevom koji se javlja ubrzo nakon prvog obroka mlijeka (dojenja).<\/p>\n

Gubitak nutrijenata je zna\u010dajan, tako da novoro\u0111en\u010de ne napreduje te se razvijaju dehidriranost, hipoglikemija i acidoza. Nakon uvo\u0111enja dijete bez laktoze proljev prestaje, dijete dobiva na tjelesnoj masi, rast i razvoj se normaliziraju. Stanje je do\u017eivotno i zahtijeva trajnu prehranu bez laktoze.<\/p>\n

Uro\u0111ena intolerancija laktoze javlja se rijetko<\/strong>, ali 65 posto odraslih osjetilo je probavne smetnje nakon konzumacije mlije\u010dnih proizvoda, tvrdi Nazareth i dodaje da se kod ve\u0107ine ljudi osjetljivost na laktozu smanjuje s godinama.<\/p>\n

Porodi\u010dno\u00a0stablo ima veliku ulogu kod naslje\u0111ivanja bolesti, upozorava Nazareth<\/strong>. Tako mo\u017eete zabilje\u017eiti sve bolesti koje su pogodile \u010dlanove va\u0161e u\u017ee i \u0161ire porodice\u00a0te tako prepoznati genetske predispozicije za neka stanja. No neke bolesti mogu ostati \u201cprikrivene\u201d i tokom nekoliko nara\u0161taja pa ih je nemogu\u0107e otkriti ovom metodom.<\/p>\n

\"SlikovniNasljedne su i dugotrajne glavobolje<\/h2>\n

Sklonost dugotrajnim i te\u0161kim glavoboljama popra\u0107enim mu\u010dninom nasljedna je u \u010dak 70 do 80 posto slu\u010dajeva<\/strong>, tvrdi dr. Kate Henry sa Univerziteta New York. Znanstvenici su otkrili kako gen naziva tresk<\/strong> izaziva pojavu migrena, a on se \u010desto naslije\u0111uje od roditelja.<\/p>\n

Bolesti srca preuzimamo od majke<\/h2>\n

Ako je va\u0161a majka imala probleme sa srcem, imate 20 posto ve\u0107u vjerovatnost da \u0107ete ih imati i vi<\/strong>, otkrile su \u010detiri odvojene nau\u010dne\u00a0studije. Na\u010din na koji prija\u0161nji infarkt majke uti\u010de na na\u0161u sklonost njemu nije u potpunosti razja\u0161njen, no ipak je o\u010dit, tvrde stru\u010dnjaci.<\/p>\n

Nismo po\u0161te\u0111eni ni psihi\u010dkih bolesti<\/h2>\n

Oko 10 posto iznosi vjerovatnost da \u0107ete naslijediti sklonost obolijevanju od depresije, otkrio je ameri\u010dki Institut za mentalno zdravlje. Stru\u010dnjaci obja\u0161njavaju kako je depresija samo jedna od psihi\u010dkih bolesti koje se mogu naslijediti, uz bipolarni poreme\u0107aj i shizofreniju.\u00a0<\/strong><\/p>\n<\/div>\n

24sata.hr<\/a><\/p>\n

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Jabuka ne pada daleko od stabla pa od roditelja mo\u017eemo naslijediti brojne fizi\u010dke osobine, ali i bolesti. Od svakog roditelja \u201ckupimo\u201d po dvije kopije svakoga gena, a mutacija odre\u0111enih gena glavni je okida\u010d za nasljedne bolesti. Prvi na popisu je…<\/p>\n

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